Research line:

Early development of the amniote embryo

Principal Investigator: Federica Bertocchini, Ramón y Cajal researcher

 

Other personnel:

• Lucía Carrera Fernández, predoctoral
• Marisa Junco Martín, lab technician

 

Web site:

 http://federicabertocchini.com/

 

 

Research interests:

 

• Axis formation 
• Primordial Germ Cells specification and maintenance in the early embryo
• Early endoderm formation and patterning
• Chick Embryonic Stem Cells (cESC)

 

Funding:  

• Ministry of Science and Innovation, Government of Spain, National Plan I+D+I for not oriented research. Grant number: BFU2010-19656 (2010)
• Fundacion Ramon Areces, XIV Concurso Ciencias de la Vida y de la Materia (2012)
• Royal Society International exchange grant with Dr. S. Srinivas, Oxford University, Oxford, UK (07/2013-06/2014)

 

Publications:

 

• Bertocchini, F., Alev, C., Yukiko Nakaya, Y. and Sheng, G. “A little winning streak: the reptilian-eye view of gastrulation in birds”. Development Growth and Differentiation, 2013, 55(1):52-9 (corresponding author)
• Bertocchini F. * and Stern, C.D.* “GATA2 provides an early anterior bias and uncovers a global positioning system for polarity in the amniote embryo” Development 139, 4232-4238, 2012 (*corresponding author)
• Bertocchini F. and Stern, C.D. “A differential screen for genes expressed in the extraembryonic endodermal layer of pre-primitive streak stage chick embryos reveals expression of Apolipoprotein A1 in hypoblast, endoblast and endoderm”, Gene Expr Patterns 8, 477-480, 2008
• Voiculescu, O., Bertocchini, F., Keller, R. and Stern, C.D. “The amniote primitive streak is defined by epithelial cell intercalation before gastrulation”, Nature 449, 1049-1052, 2007
• Lavial, F. Acloque, H., Bertocchini, F., MacLeod, D.J., Boast, S., Bachelard, E., Montillet, G., Thenot, S., Sang, H.M., Stern, C.D., Samar, J. and Pain, B. “The Oct4 homologue PouV and Nanog regulate pluripotency in chicken embryonic stem cells”, Development 134, 3549-3563, 2007.
• Bertocchini, F., I. Skromne, L. Wolpert and Stern, C.D. “Determination of embryonic polarity in a regulative system: evidence for endogenous inhibitors acting sequentially during primitive streak formation in the chick embryo” Development 131, 3381-3390, 2004
• Bertocchini, F. and Stern, C.D. “The hypoblast of the chick embryo positions the primitive streak by antagonizing Nodal signaling”, Developmental Cell 3, 735–744, 2002.

 

Contacto:

Dra. Federica Bertocchini

Phone: (+34) 942 206799 (ext. 127) / Fax : (+34) 942 266399

Email: bertocchinif@unican.es

Mailing address: IBBTEC. C/ Albert Einstein 22, PCTCAN, 39011 Santander